CD25 Antikörper (APC)

Produktnummer ABIN264237

Dieser Anti-CD25 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD25 in FACS. Geeignet für Human.

Kurzübersicht für CD25 Antikörper (APC) (ABIN264237)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD25 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: 1TYV

Produktdetails anti-CD25 Antikörper (APC)

Spezifität: Identification of human receptor for Interleukin-2 (IL-2R) expressing the 55,000 M.W. surface antigen. This antibody is specific for Interleukin-2 Receptor Lymphocytes.

Produktmerkmale: Synonyms: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TACantigen

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Monitoring of activated T cells in peripheral blood. Analysis of NK subsets. Study of B cell activation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: PBMC: Add 10 ul of MAB/10e6 PBMC in 100 ul PBS. Mix gently and incubate for 15 minutes at 2-8°C. Wash twice with PBS and analyze or fix with 0. 5% v/v of paraformaldehyde in PBS andanalyze.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.2 % protein carrier and 0.08 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. Do Not Freeze!
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung: CD25 / IL2RA

Hintergrund: The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55

Gen-ID: 3559

UniProt: P01589

Pathways: JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation